Modern Chemical Regulation. Practical Industry Compliance.
M8 Sustainable Chemistry supports U.S. regulatory authorities and chemical manufacturers in the design, implementation, and compliance of risk-based chemical management systems aligned with modern regulatory expectations and scientific best practices.
The Chemical Regulatory Trifecta
Effective chemical management requires understanding how regulation is written, how it is implemented, and how it impacts real-world operations. M8 Sustainable Chemistry operates across all three dimensions, government, industry, and implementation.
We serve as a bridge between regulatory policy and practical implementation, translating requirements into programs and workflows that are scientifically sound, operationally practical, and aligned with modern U.S. regulatory expectations.
Government
Industry
Government
Industry
Implementation
Implementation
With more than 30 years of global chemical regulatory and policy experience, including senior scientific and regulatory work at the U.S. Environmental Protection Agency, Leslie MacDougall brings a rare cross-sector perspective spanning government regulatory development, global industry compliance, and independent implementation advisory.
Leslie has supported the design and operationalization of chemical management frameworks, substance registration and assessment systems, and cross-border compliance programs across multiple jurisdictions. She founded M8 Sustainable Chemistry to bridge the gap between regulatory policy, scientific risk assessment, and practical industry implementation — ensuring chemical management systems are both effective and operationally achievable.
Through M8 and its regional expansion via ChemReg W.L.L., Leslie continues to support governments, regulators, and multinational manufacturers in developing and navigating modern chemical regulatory systems aligned with international best practices.
"Sustainable chemistry isn't a trade-off — it's the most rigorous standard the industry can hold itself to."
Our Services
Supporting the Full Chemical Regulatory Ecosystem
M8 Sustainable Chemistry provides advisory and implementation support across government regulatory development, industry compliance strategy, and independent technical program delivery.
Government & Regulatory Advisory
Architecting modern chemical management frameworks.
- Chemical Management Program
- Regulatory Framework Development
- Registration & Assessment Systems
- Hazard Communication Programs
- Policy Alignment & Harmonization
- Capacity Building & Training
Industry Compliance & Market Access
Streamlining chemical regulatory compliance and market access.
- Global Registration Strategy
- Compliance Audits & Due Diligence
- Product Stewardship Programs
- Classification, Labeling & SDS
- Supply Chain Compliance
- Import/Export Navigation
- Data Sharing & Compensation
Implementation & Technical Advisory
Translating regulatory policy into operational solutions.
- Risk Assessment & Testing Strategy
- Phase-Gate Regulatory Support
- CRO Selection & Study Oversight
- Compliance Program Implementation
- Training & Stakeholder Engagement
- SOP & Workflow Development
Architecting modern chemical management frameworks.
- Chemical Management Program
- Regulatory Framework Development
- Registration & Assessment Systems
- Hazard Communication Programs
- Policy Alignment & Harmonization
- Capacity Building & Training
Streamlining chemical regulatory compliance and market access.
- Global Registration Strategy
- Compliance Audits & Due Diligence
- Product Stewardship Programs
- Classification, Labeling & SDS
- Supply Chain Compliance
- Import/Export Navigation
- Data Sharing & Compensation
Translating regulatory policy into operational solutions.
- Risk Assessment & Testing Strategy
- Phase-Gate Regulatory Support
- CRO Selection & Study Oversight
- Compliance Program Implementation
- Training & Stakeholder Engagement
- SOP & Workflow Development
Publications
Global Chemical Control Handbook: A Guide to Chemical Management Programs
The business of chemicals is being impacted by measures being taken by governments as well as industry stakeholders to improve all aspects of chemical management, from production and processing to distribution, use, and disposal. Governments acros...
Read More →Think REACH Does Not Apply to Your Company? Are You Certain?
This article outlines frequent misconceptions regarding REACH obligations and provides guidance to help confirm whether companies have responsibilities under REACH.
Read More →Standardising Transport/Labelling Regulations: A way to reduce shipping costs for retail and consumer products
In the context of 2014 chemical transportation, standardizing regulations, particularly through adopting the Globally Harmonized System (GHS), significantly reduces shipping costs for retail and consumer products.
This standardization c...
Read More →Data Citation and Compensation: How REACH Compares With the FIFRA SchemeData Citation and Compensation: How REACH Compares With the FIFRA Scheme
A comparative analysis of data citation and compensation frameworks under the EU's REACH regulation and the US Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA).
Co-authored by Leslie S. MacDougall, Lisa M. Campbell, and Ruxan...
Read More →Turkey Enacts REACH-Like Chemical Program: What Stakeholders Need to Know
Turkey enacted the Inventory and Control of Chemicals Regulation (Regulation) in December 2008. The Regulation is a scaled-down version of the European Union’s Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) regulation...
Read More →Cluster of Bell's Palsy Cases Found Among Hospital EmployeesCluster of Bell's Palsy Cases Found Among Hospital Employees
A brief epidemiological report documenting an unusual cluster of Bell's palsy cases among hospital employees. Published as correspondence in Clinical Infectious Diseases, the investigation examined potential occupational or environmental factors c...
Read More →